What’s New for Dermatology Drugs in 2017-2018

The specialty of Medical Dermatology has been in a renaissance for the last decade or so because of the development of many new injectable drugs for some common complex diseases such as Psoriasis, Psoriatic Arthritis, and Atopic Dermatitis, but also for some lesser known entities which we will discuss later.

Hidradenitis Suppurativa

The name Hidradenitis Suppurativa (HS) implies that the disease involves collections of white blood cells or “pus” in and around sweat glands. However, our current understanding of HS is that it begins with blockage of hair follicles followed by inflammation and possibly infection of the associated sweat glands. The areas that are …

Can Simultaneous Psoriasis and Granuloma Annulare Annihilate Each Other?

In a previous post on this blog, I reported a patient who had psoriasis, granuloma annulare (GA), and alopecia areata. I recently saw two more cases where psoriasis was coincidentally associated with GA. Case 1. A middle-aged lady was referred by her primary care doctor for a rash on the legs. Some of …

Rash in a Patient with HIV Infection

A 50-year-old man presented  for the diagnosis and treatment of a rash on his legs and back for about 1 and 1/2 years. His past medical history was significant for HIV infection which had been treated with Highly Active Anti-Retroviral Therapy (HAART). He stated that his viral counts were undetectable and …

Coexistence of 3 Autoimmune Diseases: Granuloma Annulare and Psoriasis and Alopecia Areata

A middle-aged woman consulted me for a rash on her palms and backs of hands for several years’ duration.  The rash consisted of smooth pinkish-red bumps on the knuckles and rings and arcs on the palms with central clearing. Curiously, when the two palms were held together side-by-side, incomplete arcs formed …

Vaccinations for Childhood Diseases Is a Public Health Necessity

I’m old enough to have acquired every childhood communicable disease except for smallpox and polio. The latter diseases were already practically eradicated from earth thanks to Jenner’s original vaccine and Jonas Salk’s vaccine, respectively. In fact, the name “vaccine” comes from the name of the live virus in the smallpox …

Gluten Sensitivity and Gluten-Free Diets in Dermatology

Gluten represents a group of proteins that are found in wheat, barley, and rye. Gluten is not present in rice and oats. Celiac disease, also know as “gluten-sensitive enteropathy,” is a type of hypersensitivity or allergy to the gluten proteins that causes inflammation and damage to membranes lining the small …

Psoriasis Associated with Plaquenil (Hydroxychloroquine)

The following case studies illustrate examples where Plaquenil administration was associated with either new onset psoriasis or flaring of pre-existing psoriasis. Case 1. A middle-aged woman sought another opinion for a puzzling rash which had been seen by two dermatologists. At first, skin biopsies showed features of eczema. Subsequent biopsies …

Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists

It may surprise you to learn that anti-malarial drugs are used by dermatologists and rheumatologists. But not to treat malaria! Chloroquine and hydroxychloroquine (commonly known by its old brand-name Plaquenil) were first used to treat malaria, but the malaria-causing organism soon became resistant to them. However, during the treatment of …