Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists

It may surprise you to learn that anti-malarial drugs are used by dermatologists and rheumatologists. But not to treat malaria! Chloroquine and hydroxychloroquine

plaqueniltabs(commonly known by its old brand-name Plaquenil) were first used … Continue reading

Skin Diseases and Granulocyte White Blood Cells: Hidradenitis Suppurativa, Sweet’s Syndrome, and Pyoderma Gangrenosum

Granulocytes are the predominant white blood cells released from the bone marrow.  They are responsible for ingesting and killing or inactivating most infectious organisms, a process called phagocytosis.  The granules referred to in the name are actually the lysosomes in the cell that contain caustic and digestive enzymes. These same … Continue reading

METHOTREXATE–Reincarnation of an Old Drug

Methotrexate (MTX) is by far the most popular oral agent used by dermatologists today for psoriasis and has been so for the last 40 years.  Its epitaph was nearly written after the more potent biologic immunomodulators such as Enbrel and Humira were predicted to render MTX obsolete.  Now it appears that … Continue reading