Can Simultaneous Psoriasis and Granuloma Annulare Annihilate Each Other?

In a previous post on this blog, I reported a patient who had psoriasis, granuloma annulare (GA), and alopecia areata. I recently saw two more cases where psoriasis was coincidentally associated with GA.

Case 1. A middle-aged lady was referred by her primary care doctor for a rash on the legs. Some of … Continue reading

Rash in a Patient with HIV Infection

A 50-year-old man presented  for the diagnosis and treatment of a rash on his legs and back for about 1 and 1/2 years. His past medical history was significant for HIV infection which had been treated with Highly Active Anti-Retroviral Therapy (HAART). He stated that his viral counts were undetectable and … Continue reading

Psoriasis Associated with Plaquenil (Hydroxychloroquine)

The following case studies illustrate examples where Plaquenil administration was associated with either new onset psoriasis or flaring of pre-existing psoriasis.

Case 1. A middle-aged woman sought another opinion for a puzzling rash which had been seen by two dermatologists. At first, skin biopsies showed features of eczema. Subsequent biopsies … Continue reading

Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists

It may surprise you to learn that anti-malarial drugs are used by dermatologists and rheumatologists. But not to treat malaria! Chloroquine and hydroxychloroquine

plaqueniltabs(commonly known by its old brand-name Plaquenil) were first used … Continue reading

Do I Have Lupus, Doctor?

Systemic Lupus Erythematosus (SLE) is a devastating autoimmune disease that can affect nearly every organ system in the body. The skin is no exception, and in fact, may be involved in 70-80% of cases. An equal number of patients may experience abnormal sun or ultraviolet light sensitivity, called photosensitivity. There are … Continue reading

DERMATOMYOSITIS

Dermatomyositis is one of the autoimmune connective tissue diseases. The name is derived from dermato=skin, myo=muscle, and itis=inflammation. Thus, inflammation of unknown cause leads to a distinctive skin rash and weakness and tenderness of the muscles, particularly of the hip and shoulder girdles.  Dermatomyositis (DM) affects women more than men (about 2 to 1), usually … Continue reading

Granuloma Annulare and Necrobiosis Lipoidica

Granuloma annulare (GA) is a skin disease commonly encountered in our clinic, either as an initial self-motivated visit or on consultation from another physician. The rash consists of small smooth bumps that may be skin-colored, pink, reddish-purple, brownish-orange. … Continue reading

How Efficient Is Your Dermatologist? Example from My Practice-Eczema or Ringworm

Dermatologists can be incredibly efficient and cost-effective in their practices because of their background and training in medicine and surgical procedures. We are not often acknowledged or appreciated for this by health insurance companies. The skin is the largest  organ in the body and plays an important role in immune … Continue reading

Accutane or Isotretinoin for Severe Acne: Update on Side-Effects

One of the most important drugs used in Dermatology today is Isotretinoin, also known as Accutane, for severe acne.  It is the only medication capable of curing the most severe forms of scarring cystic acne.  AccutaneBottles

Accutane is the brand … Continue reading

METHOTREXATE–Reincarnation of an Old Drug

Methotrexate (MTX) is by far the most popular oral agent used by dermatologists today for psoriasis and has been so for the last 40 years.  Its epitaph was nearly written after the more potent biologic immunomodulators such as Enbrel and Humira were predicted to render MTX obsolete.  Now it appears that … Continue reading