Can Simultaneous Psoriasis and Granuloma Annulare Annihilate Each Other?

In a previous post on this blog, I reported a patient who had psoriasis, granuloma annulare (GA), and alopecia areata. I recently saw another case where psoriasis was coincidentally associated with GA.

Case. A middle-aged lady was referred by her primary care doctor for a rash on the legs. Some of the … Continue reading

Hidradenitis Suppurativa

HidrenitisAxillaThe name Hidradenitis Suppurativa (HS) implies that the disease involves collections of white blood cells or “pus” in and around sweat glands. However, our current understanding of HS is that it begins with blockage of hair follicles followed by inflammation and possibly infection … Continue reading

Coexistence of 3 Autoimmune Diseases: Granuloma Annulare and Psoriasis and Alopecia Areata

A middle-aged woman consulted me for a rash on her palms and backs of hands for several years’ duration.  The rash consisted of smooth pinkish-red bumps on the knuckles and rings and arcs on the palms with central clearing. … Continue reading

Vaccinations for Childhood Diseases Is a Public Health Necessity

syringesI’m old enough to have acquired every childhood communicable disease except for smallpox and polio. The latter diseases were already practically eradicated from earth thanks to Jenner’s original vaccine and Jonas Salk’s vaccine, respectively. In fact, the name “vaccine” comes from the … Continue reading

Gluten Sensitivity and Gluten-Free Diets in Dermatology

breadpastaGluten represents a group of proteins that are found in wheat, barley, and rye. Gluten is not present in rice and oats. Celiac disease, also know as “gluten-sensitive enteropathy,” is a type of hypersensitivity or allergy to the gluten proteins that … Continue reading

Psoriasis Associated with Plaquenil (Hydroxychloroquine)

The following case studies illustrate examples where Plaquenil administration was associated with either new onset psoriasis or flaring of pre-existing psoriasis.

Case 1. A middle-aged woman sought another opinion for a puzzling rash which had been seen by two dermatologists. At first, skin biopsies showed features of eczema. Subsequent biopsies … Continue reading

Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists

It may surprise you to learn that anti-malarial drugs are used by dermatologists and rheumatologists. But not to treat malaria! Chloroquine and hydroxychloroquine

plaqueniltabs(commonly known by its old brand-name Plaquenil) were first used to treat malaria, but the malaria-causing organism soon … Continue reading

Do I Have Lupus, Doctor?

Systemic Lupus Erythematosus (SLE) is a devastating autoimmune disease that can affect nearly every organ system in the body. The skin is no exception, and in fact, may be involved in 70-80% of cases. An equal number of patients may experience abnormal sun or ultraviolet light sensitivity, called photosensitivity. There are … Continue reading


Dermatomyositis is one of the autoimmune connective tissue diseases. The name is derived from dermato=skin, myo=muscle, and itis=inflammation. Thus, inflammation of unknown cause leads to a distinctive skin rash and weakness and tenderness of the muscles, particularly of the hip and shoulder girdles.  Dermatomyositis (DM) affects women more than men (about 2 to 1), usually … Continue reading